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. 2019 Dec 13;10:1433. doi: 10.3389/fphar.2019.01433

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Copyright © 2019 Zhong, Han, Zhang, Xiao, Chen, Zhang, Hu and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of salidroside on TH immunoreactivity in the SNpc after MCAO in rats. (A, B) TH immunohistochemical staining in the dopaminergic mesencephalic nuclei of the ipsilateral SNpc. Scale bar, 100 µm (A) and 50 µm (B). (C) TH immunofluorescence staining in the dopaminergic mesencephalic nuclei of the ipsilateral SNpc. Scale bar, 50 µm. (D) Schematic diagram of rat brain Arrow indicates SNpc. (E) Immunoreactivity area percent of TH-positive expression in the SNpc after cerebral ischemia/reperfusion in rats. Values are all represented as the mean ± SEM (n = 5 rats per group). *p < 0.05 compared with the sham group; ^# p < 0.05 compared with the MCAO group. MCAO middle cerebral artery occlusion, SEM standard error of the mean, SNpc substantia nigra pars compacta, TH tyrosine hydroxylase.