Table 1. Baseline clinical and angiographic characteristics of patients according to baseline SS.
| Total population | Low SS (729 patients) | Intermediate SS (362 patients) | High SS (157 patients) | p value | ||
|---|---|---|---|---|---|---|
| Age (years) | 65.7±10.2 | 64.6±10.2 | 66.5±10.2 | 68.8±9.3 | <0.001 | |
| Male (sex) | 819 (65.6) | 476 (65.3) | 249 (68.8) | 94 (59.9) | 0.139 | |
| Body mass index (kg/m2) | 24.5±3.2 | 24.7±3.3 | 24.5±3.0 | 24.0±3.1 | 0.069 | |
| Diabetes | 600 (48.1) | 353 (48.4) | 168 (46.4) | 79 (50.3) | 0.686 | |
| Hypertension | 852 (68.3) | 499 (68.4) | 246 (68.0) | 107 (68.2) | 0.986 | |
| Dyslipidemia | 468 (37.5) | 272 (37.3) | 137 (37.8) | 59 (37.6) | 0.985 | |
| Chronic renal failure | 79 (6.3) | 41 (5.6) | 22 (6.1) | 16 (10.2) | 0.100 | |
| Peripheral vascular disease | 38 (3.0) | 19 (2.6) | 14 (3.9) | 5 (3.2) | 0.518 | |
| Previous myocardial infarction | 87 (7.0) | 45 (6.2) | 29 (8.0) | 13 (8.3) | 0.420 | |
| Previous PCI | 209 (16.7) | 131 (18.0) | 53 (14.6) | 25 (15.9) | 0.366 | |
| Previous congestive heart failure | 54 (4.3) | 25 (3.4) | 18 (5.0) | 11 (7.0) | 0.105 | |
| Previous CVA | 165 (13.2) | 104 (14.3) | 37 (10.2) | 24 (15.3) | 0.128 | |
| Smoking status* | 26.8/18.7/53.4 | 27.8/18.7/53.4 | 26.7/15.7/57.6 | 22.1/20.1/57.8 | 0.386 | |
| Current smoker | 328 (26.8) | 199 (27.8) | 95 (26.7) | 34 (22.1) | 0.346 | |
| Family history of CAD | 63 (6.7) | 47 (6.4) | 27 (7.5) | 9 (5.7) | 0.848 | |
| Clinical diagnosis† | 39.2/40.6/20.2 | 40.7/42.2/17.1 | 37.3/39.0/23.7 | 36.5/37.2/26.3 | 0.089 | |
| Initial presentation as ACS | 751 (60.2) | 427 (58.6) | 225 (62.2) | 99 (63.1) | 0.384 | |
| LV ejection fraction | 57.5±11.7 | 59.2±10.9 | 56.5±11.7 | 52.7±13.2 | <0.001 | |
| Angiographic findings | ||||||
| Left main disease | 287 (23.0) | 154 (21.1) | 85 (23.5) | 48 (30.6) | 0.037 | |
| Bifurcation | 361 (28.9) | 188 (25.8) | 120 (33.1) | 53 (33.8) | 0.015 | |
| No. of treated vessels | <0.001 | |||||
| 1 vessel treated | 648 (51.9) | 420 (57.6) | 161 (44.5) | 67 (42.7) | ||
| 2 vessels treated | 471 (37.7) | 259 (35.5) | 149 (41.2) | 63 (40.1) | ||
| 3 vessels treated | 129 (10.3) | 50 (6.9) | 52 (14.4) | 27 (17.2) | ||
| No. of stents placed | 2.1±1.1 | 1.9±0.9 | 2.4±1.2 | 2.6±1.4 | <0.001 | |
| Total length of stents (mm) | 52.3±31.7 | 44.5±24.4 | 61.2±35.4 | 67.7±40.6 | <0.001 | |
| SS | 21.1±9.6 | 14.5±5.2 | 27.1±2.8 | 38.0±4.9 | <0.001 | |
| Residual SS | 9.3±7.9 | 5.9±5.0 | 12.1±7.3 | 18.4±10.0 | <0.001 | |
| Complete revascularization | 178 (14.3) | 157 (21.5) | 19 (5.2) | 2 (1.3) | <0.001 | |
Data are shown as mean±standard deviation or number (%). Complete revascularization was defined as a residual SS of 0.
ACS = acute coronary syndrome; CAD = coronary artery disease; CVA = cerebrovascular accident; LV = left ventricular; PCI = percutaneous coronary intervention; SS = SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery score.
*Smoking: current smokers/ex-smokers/never smokers; †Clinical diagnosis: stable angina/unstable angina/non-ST elevation myocardial infarction.