Figure 3. Gal-3 target spot TXNIP/NLRP3.
Gene chip (A), analysis chart (B), network signal diagram (C), structural formula of Gal-3 (D), Gal-3 induced Gal-3, TXNIP and NLRP3 protein expressions in in vitro model of SCI (E–H), GB1107 suppressed Gal-3, TXNIP and NLRP3 protein expressions in rat model of SCI (I–L). Negative, negative mimic group; Gal-3, overexpression of Gal-3 group; Control, control sham group; SCI, SCI model group; SCI+GB1107, SCI model by GB1107 group. **P<0.01 compared with negative or control group, ##P<0.01 compared with SCI model group.