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. 2019 Dec 16;39(12):BSR20192368. doi: 10.1042/BSR20192368

Figure 6. ROS regulates the effects of Gal-3 on neuroinflammation in vitro model.

Figure 6

Expression of TXNIP and NLRP3 proteins (AC), IL-1β levels (D) by overexpression of ROS; TXNIP and NLRP3 protein expressions (EG), IL-1β levels (H) by ROS inhibitor. Control, control group; LPS, SCI model group; LPS+si-Gal-3, SCI model by si-Gal-3 group; LPS+si-Gal-3+H2O2, SCI model by si-Gal-3 and H2O2 group; LPS+ROS inhibitor, SCI model by ROS inhibitor group; LPS+ROS inhibitor+Gal-3, SCI model by ROS inhibitor and Gal-3 group. **P<0.01 compared with control group, ##P<0.01 compared with SCI model group; ***P<0.01 compared with LPS+ROS inhibitor or LPS+si-Gal-3 group.