Expression of TXNIP and NLRP3 proteins (A–C), IL-1β levels (D) by overexpression of ROS; TXNIP and NLRP3 protein expressions (E–G), IL-1β levels (H) by ROS inhibitor. Control, control group; LPS, SCI model group; LPS+si-Gal-3, SCI model by si-Gal-3 group; LPS+si-Gal-3+H2O2, SCI model by si-Gal-3 and H2O2 group; LPS+ROS inhibitor, SCI model by ROS inhibitor group; LPS+ROS inhibitor+Gal-3, SCI model by ROS inhibitor and Gal-3 group. **P<0.01 compared with control group, ##P<0.01 compared with SCI model group; ***P<0.01 compared with LPS+ROS inhibitor or LPS+si-Gal-3 group.