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. 2019 Dec 16;39(12):BSR20192368. doi: 10.1042/BSR20192368

Figure 8. The inhibition of NLRP3 reduced the effect of Gal-3 on neuroinflammation in vitro model.

Figure 8

NLRP3 protein expressions (A,B), IL-1β levels (C) by overexpression of NLRP3; NLRP3 protein expressions (D,E), IL-1β levels (F) by down-regulation of NLRP3; Control, control group; LPS, SCI model group; LPS+si-NLRP3, SCI model by si-NLRP3 group; LPS+si-NLRP3+Gal-3, SCI model by si-NLRP3+Gal-3 group; LPS+si-Gal-3, SCI model by i-Gal-3 group; LPS+si-Gal-3+ NLRP3, SCI model by si-Gal-3+ NLRP3 group. **P<0.01 compared with control group, ##P<0.01 compared with SCI model group; ***P<0.01 compared with LPS+si-NLRP3 and LPS+si-Gal-3 groups.