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. 2019 Dec 17;39(12):BSR20191454. doi: 10.1042/BSR20191454

Table 4. Logistic regression analysis of five SNPs in three genetic models.

SNP Genetic model Univariate Adjusted1
OR (95% CI) P-value OR (95% CI) P-value
rs1801131 Additive CC vs AA 1.13 (0.62–2.04) 0.690 1.32 (0.45–3.86) 0.608
AC vs AA 1.08 (0.88–1.33) 0.462 0.92 (0.64–1.33) 0.667
Dominant CC+AC vs AA 1.09 (0.89–1.32) 0.425 0.95 (0.67–1.35) 0.782
Recessive CC vs AC+AA 1.11 (0.61–2.00) 0.736 1.35 (0.47–3.92) 0.579
rs1801133 Additive TT vs CC 0.89 (0.69–1.14) 0.340 1.24 (0.81–1.92) 0.324
CT vs CC 0.93 (0.74–1.17) 0.540 1.38 (0.92–2.06) 0.117
Dominant TT+CT vs CC 0.91 (0.74–1.17) 0.405 1.32 (0.91–1.93) 0.143
Recessive TT vs CT+CC 0.93 (0.77–1.13) 0.464 1.00 (0.71–1.40) 0.999
rs9651118 Additive CC vs TT 0.93 (0.66–1.32) 0.679 0.77 (0.41–1.46) 0.425
TC vs TT 0.94 (0.78–1.13) 0.496 0.81 (0.58–1.12) 0.196
Dominant CC+TC vs TT 0.94 (0.79–1.12) 0.464 0.80 (0.59–1.10) 0.166
Recessive CC vs TC+TT 0.95 (0.68–1.34) 0.786 0.85 (0.45–1.58) 0.601
rs117353193 Additive AA vs GG - - - -
GA vs GG 0.99 (0.74–1.33) 0.955 0.59 (0.33–1.04) 0.069
Dominant AA+GA vs GG 0.98 (0.74–1.31) 0.910 0.56 (0.32–0.99) 0.0452
Recessive AA vs GA+GG - - - -
rs9916351 Additive TT vs CC 1.25 (0.97–1.61) 0.091 1.13 (0.68–1.89) 0.644
CT vs CC 1.13 (0.89–1.44) 0.304 0.86 (0.61–1.20) 0.552
Dominant TT+CT vs CC 0.88 (0.73–1.06) 0.176 0.91 (0.66–1.25) 0.552
Recessive TT vs CT+CC 0.85 (0.68–1.06) 0.155 1.23 (0.76–1.99) 0.398
1

Adjusted for gender, age, waistline, BMI, smoking, FBG, TC and TG.

2Significant difference (P<0.05).