Table 4. Logistic regression analysis of five SNPs in three genetic models.
SNP | Genetic model | Univariate | Adjusted1 | |||
---|---|---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |||
rs1801131 | Additive | CC vs AA | 1.13 (0.62–2.04) | 0.690 | 1.32 (0.45–3.86) | 0.608 |
AC vs AA | 1.08 (0.88–1.33) | 0.462 | 0.92 (0.64–1.33) | 0.667 | ||
Dominant | CC+AC vs AA | 1.09 (0.89–1.32) | 0.425 | 0.95 (0.67–1.35) | 0.782 | |
Recessive | CC vs AC+AA | 1.11 (0.61–2.00) | 0.736 | 1.35 (0.47–3.92) | 0.579 | |
rs1801133 | Additive | TT vs CC | 0.89 (0.69–1.14) | 0.340 | 1.24 (0.81–1.92) | 0.324 |
CT vs CC | 0.93 (0.74–1.17) | 0.540 | 1.38 (0.92–2.06) | 0.117 | ||
Dominant | TT+CT vs CC | 0.91 (0.74–1.17) | 0.405 | 1.32 (0.91–1.93) | 0.143 | |
Recessive | TT vs CT+CC | 0.93 (0.77–1.13) | 0.464 | 1.00 (0.71–1.40) | 0.999 | |
rs9651118 | Additive | CC vs TT | 0.93 (0.66–1.32) | 0.679 | 0.77 (0.41–1.46) | 0.425 |
TC vs TT | 0.94 (0.78–1.13) | 0.496 | 0.81 (0.58–1.12) | 0.196 | ||
Dominant | CC+TC vs TT | 0.94 (0.79–1.12) | 0.464 | 0.80 (0.59–1.10) | 0.166 | |
Recessive | CC vs TC+TT | 0.95 (0.68–1.34) | 0.786 | 0.85 (0.45–1.58) | 0.601 | |
rs117353193 | Additive | AA vs GG | - | - | - | - |
GA vs GG | 0.99 (0.74–1.33) | 0.955 | 0.59 (0.33–1.04) | 0.069 | ||
Dominant | AA+GA vs GG | 0.98 (0.74–1.31) | 0.910 | 0.56 (0.32–0.99) | 0.0452 | |
Recessive | AA vs GA+GG | - | - | - | - | |
rs9916351 | Additive | TT vs CC | 1.25 (0.97–1.61) | 0.091 | 1.13 (0.68–1.89) | 0.644 |
CT vs CC | 1.13 (0.89–1.44) | 0.304 | 0.86 (0.61–1.20) | 0.552 | ||
Dominant | TT+CT vs CC | 0.88 (0.73–1.06) | 0.176 | 0.91 (0.66–1.25) | 0.552 | |
Recessive | TT vs CT+CC | 0.85 (0.68–1.06) | 0.155 | 1.23 (0.76–1.99) | 0.398 |
Adjusted for gender, age, waistline, BMI, smoking, FBG, TC and TG.
2Significant difference (P<0.05).