Table 2.
Multivariate analysis of demographics and risk factors with the thickness of INL-RPE layer.
| Central subfield | Average Inner Subfield | Average Outer Subfield | Total Average | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β | B | 95% CI | P | β | B | 95% CI | P | β | B | 95% CI | P | β | B | 95% CI | P | |
| Age | −0.011 | −0.023 | (−0.048, 0.002) | 0.076 | −0.020 | −0.028 | (−0.045, −0.011) | 0.001 | −0.053 | −0.058 | (−0.071, −0.045) | <0.001 | −0.041 | −0.048 | (−0.063, −0.034) | <0.001 |
| Sex | ||||||||||||||||
| Male | Ref | Ref | Ref | Ref | ||||||||||||
| Female | −1.944 | (−2.479, −1.408) | <0.001 | −1.704 | (−2.060, −1.347) | <0.001 | −1.655 | (−1.938, −1.373) | <0.001 | −1.684 | (−1.988, −1.381) | <0.001 | ||||
| Race | ||||||||||||||||
| White | Ref | Ref | Ref | Ref | ||||||||||||
| Chinese | −3.903 | (−7.081, −0.726) | 0.016 | −0.831 | (−2.959, 1.297) | 0.444 | −0.442 | (−2.127, 1.243) | 0.607 | −0.28 | (−2.093, 1.534) | 0.762 | ||||
| Asian | −5.868 | (−7.070, −4.665) | <0.001 | −3.581 | (−4.382, −2.780) | <0.001 | −2.804 | (−3.437, −2.170) | <0.001 | −3.01 | (−3.691, −2.328) | <0.001 | ||||
| Black | −11.438 | (−12.603, −10.273) | <0.001 | −7.688 | (−8.465, −6.911) | <0.001 | −6.122 | (−6.738, −5.505) | <0.001 | −6.501 | (−7.164, −5.837) | <0.001 | ||||
| Mixed/Others | −4.286 | (−5.530, −3.042) | <0.001 | −2.826 | (−3.657, −1.996) | <0.001 | −2.426 | (−3.084, −1.768) | <0.001 | −2.6 | (−3.308, −1.892) | <0.001 | ||||
| Smoking status | ||||||||||||||||
| Never | Ref | Ref | Ref | Ref | ||||||||||||
| Previous | 0.588 | (0.187, 0.988) | 0.004 | 0.279 | (0.012, 0.546) | 0.041 | 0.093 | (−0.118, 0.304) | 0.388 | 0.157 | (−0.070, 0.384) | 0.176 | ||||
| Current | −0.08 | (−0.729, 0.568) | 0.808 | −0.298 | (−0.729, 0.134) | 0.176 | −0.558 | (−0.899, −0.217) | 0.001 | −0.54 | (−0.907, −0.173) | 0.004 | ||||
| SBP (per 10 mmHg) | −0.162 | −0.14 | (−0.25, −0.04) | 0.007 | −0.105 | −0.06 | (−0.13, 0.01) | 0.081 | −0.208 | −0.1 | (−0.15, −0.04) | 0.001 | −0.185 | −0.09 | (−0.15, −0.03) | 0.002 |
| Refraction (per 1D) | 0.011 | 0.121 | (0.004, 0.238) | 0.042 | 0.087 | 0.619 | (0.541, 0.697) | <0.001 | 0.130 | 0.729 | (0.667, 0.791) | <0.001 | 0.113 | 0.683 | (0.617, 0.750) | <0.001 |
| IOP cornea compensated (mmHg) | 0.023 | 0.135 | (0.065, 0.206) | <0.001 | 0.013 | 0.049 | (0.002, 0.096) | 0.039 | 0.012 | 0.037 | (−0.000, 0.074) | 0.052 | 0.013 | 0.043 | (0.003, 0.083) | 0.033 |
| Corneal hysteresis | −0.003 | −0.029 | (−0.137, 0.080) | 0.606 | 0.008 | 0.046 | (−0.026, 0.118) | 0.213 | 0.016 | 0.075 | (0.018, 0.132) | 0.01 | 0.014 | 0.072 | (0.010, 0.133) | 0.022 |
*Adjusted for age, gender, ethnicity, townsend deprivation index, height, smoking status, systolic blood pressure, refraction, IOP corneal compensated, and corneal hysteresis.
β = standardised beta; B = unstandardised beta; P = P value.