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. 2019 Dec 19;9:19429. doi: 10.1038/s41598-019-54542-y

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© The Author(s) 2019, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Identification, sequence, and reference number of e-miRNAs. Identification, sequence, and reference number of the 13 e-miRNAs with the highest absolute coefficients in principal component 3 with a color scale quantified by log₂ fold change (FC) on the left, representing the degree of the upexpression (in red) and the downexpression (in green) of these e-miRNAs in the blood samples from the non-responders