Fig. 2. Somatic mutations in the epithelial component of adenomyosis lesions.
a, b HE staining of epithelial cells from adenomyosis Patient #6 (a) before and (b) after isolation by laser capture microdissection (LCM). Scale bars, 100 μm. c–e Quantification of VAF as determined by TDS of the indicated genes in peripheral blood (Blood), frozen adenomyosis lesions (Bulk-A), LCM-acquired epithelial component of adenomyosis (LCM-A), or LCM-acquired adjacent muscle cells (LCM-ADJ) from the indicated patients.