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. 2019 Dec 19;10:5785. doi: 10.1038/s41467-019-13708-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Left panel: coronal plane (top) and sagittal plane (bottom) schemes indicating the sites of multi-regional adenomyosis samples (1–6) and adjacent histologically normal myometrium (NM) that were acquired from Patient #28 and subjected to mutational profiling. R, right; L, left. Right panel: VAFs of mutations in the indicated genes in the indicated multi-regional samples profiled for each individual adenomyosis lesion, NM, or peripheral blood (B) sample from Patient #28. VAF values are shown using a color scale. b, c Top panels: sagittal plane schemes indicating the sites of multi-regional adenomyosis samples plus NM and leiomyoma (LM) samples that were acquired from Patient #29 (b) or Patient #5 (c) and subjected to mutational profiling. Bottom panels: analysis of VAFs for the samples in the top panels as for a. For a–c, raw VAF values (%) for each sample are shown in Supplementary Data 14–16.