Table 1.
TopControl-assigned scores of 17 disease-associated genes and miRNAs reported in DisGeNET and HMDD databases that belong to the full co-regulatory network for the DE genes of the LIHC dataset constructed by TFmiR.
| gene | D | hub | mds | mcds | core | LFC |
|---|---|---|---|---|---|---|
| E2F1 | 25 | 1 | 1 | 1 | 3 | 3.76 |
| ESR1 | 9 | 1 | 1 | 1 | 3 | 2.19 |
| JUN | 33 | 1 | 1 | 1 | 3 | 1.39 |
| MYC | 18 | 1 | 1 | 1 | 3 | 1.07 |
| hsa-let-7b | 47 | 1 | 1 | 1 | 3 | — |
| hsa-mir-29a | 21 | 1 | 1 | 1 | 3 | — |
| FOXM1 | 3 | 0 | 1 | 1 | 2 | 3.69 |
| FOS | 23 | 1 | 0 | 1 | 2 | 2.93 |
| CEBPD | 1 | 0 | 1 | 1 | 2 | 1.3 |
| PDGFB | 1 | 0 | 1 | 1 | 2 | 1.11 |
| SREBF2 | 3 | 0 | 1 | 1 | 2 | 0.68 |
| NFE2L2 | 4 | 0 | 1 | 1 | 2 | 0.66 |
| TERT | 6 | 1 | 0 | 0 | 1 | 9.17 |
| RRM2 | 2 | 0 | 0 | 1 | 1 | 2.98 |
| AR | 3 | 0 | 1 | 0 | 1 | 1 |
| HTATIP2 | 2 | 0 | 0 | 1 | 1 | 0.68 |
| CCND1 | 12 | 1 | 0 | 0 | 1 | 0.67 |
The candidates with the highest scores are at the top of the table and sorted by LFC in case of a similar score. D stands for the degree of the node and LFC for log2(fold change) of expression.