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. 2019 Dec 19;9:19472. doi: 10.1038/s41598-019-55954-6

Table 2.

TopControl-assigned scores for 33 disease-associated genes and miRNAs reported in DisGeNET and HMDD databases that belong to the constructed TFmiR complete network for the BRCA dataset, see Table 1.

gene D hub mds mcds score LFC
ESR2 7 1 1 1 3 2.58
FOS 20 1 1 1 3 2.47
E2F1 25 1 1 1 3 2.34
ESR1 19 1 1 1 3 1.79
JUN 45 1 1 1 3 1.6
STAT5A 7 1 1 1 3 1.6
ETS2 6 1 1 1 3 1.15
TFAP2A 24 1 1 1 3 0.9
hsa-mir-21 44 1 1 1 3
hsa-mir-146a 31 1 1 1 3
WT1 2 0 1 1 2 5.39
IFNB1 9 1 0 1 2 4.13
FOXM1 1 0 1 1 2 3.54
KIT 6 1 0 1 2 2.79
IL6 7 1 0 1 2 2.76
FOXA1 3 0 1 1 2 1.87
RARB 6 1 1 0 2 1.1
TRERF1 1 0 1 1 2 1.08
HEY2 1 0 1 1 2 1.06
MEIS1 1 0 1 1 2 1.01
NR2F6 2 0 1 1 2 1
KRAS 1 0 1 1 2 0.83
AR 5 0 1 1 2 0.63
ERBB2 6 1 0 0 1 1.89
BRCA2 4 0 0 1 1 1.81
AFP 1 0 1 0 1 1.43
EGFR 8 1 0 0 1 1.4
PDGFA 2 0 0 1 1 1.33
BRCA1 5 0 0 1 1 1.24
PARP1 1 0 1 0 1 1.2
CCND1 15 1 0 0 1 1.01
PGR 5 0 0 1 1 0.87
ZEB1 1 0 1 0 1 0.72