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. 2019 Dec 19;9:19431. doi: 10.1038/s41598-019-55942-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in intramyocellular acetylcarnitine (AcCtn) concentrations of seven patients with GHD (right) and seven CS (left). Intramyocellular AcCtn concentrations were measured by proton magnetic resonance spectroscopy (¹H-MRS) at baseline (0 h), 2 hours after moderately intense exercise (2 h), and 24 hours post-exercise (24 h). Changes of AcCtn concentrations over time did not significantly differ between GHD patients and CS (ANOVA p for group = 0.45). Bars, boxes and whiskers represent median, IQR and range. GHD = growth hormone deficiency, CS = control subjects.