Table 2.

Summary of Clinic Chemistry Measures in Wild Type C57BL/6J Mice Treated i.v. with 4.3E+14 vg/kg rAAVrh74.MCK.GALGT2

Clinic Chemistry Measures	Week 4						Week 12
	Vehicle			Test Article			Vehicle			Test Article
	Mean	SD	n	Mean	SD	n	Mean	SD	n	Mean	SD	n
Alkaline phosphatase (U/L)	65.1	15.7	7	556.3	65.0	7	66.1	12.5	7	493.7	85.2	7
Alanine aminotransferase (U/L)	32.4	18.3	7	35.0	10.6	7	38.6	16.0	7	29.0	10.0	7
Aspartate aminotransferase (U/L)	279.9	347.3	7	298.6	279.9	7	245.9	155.4	7	113.7	79.2	7
Blood urea nitrogen (mg/dL)	29.6	1.4	7	26.3	5.0	7	35.3	5.6	7	27.9	1.1	7
Creatine kinase (U/L)	5,365.0	7,015.6	6	6,294.8	4,435.5	7	6,661.4	6,493.7	7	775.6	194.3	7
Creatinine (mg/dL)	0.3	0.1	7	0.2	0.1	7	0.2	0.0	7	0.2	0.0	7
Direct bilirubin (mg/dL)	0.0	0.1	6	0.1	0.1	6	0.0	0.0	7	0.0	0.0	7
Gamma-glutamyl transferase (U/L)	0.0	0.0	7	0.1	0.4	7	0.0	0.0	7	0.7	0.8	7
Glucose (mg/dL)	351.6	65.9	5	368.1	69.7	7	216.0	95.2	7	312.0	169.6	7
Total bilirubin (mg/dL)	0.5	0.3	7	0.5	0.1	7	0.3	0.2	7	0.2	0.0	7
Total protein (g/dL)	4.4	0.3	5	4.8	0.2	7	4.8	0.4	7	4.5	0.2	7
Calcium (mg/dL)	N/A	N/A	N/A	N/A	N/A	N/A	9.0	0.5	6	9.3	0.4	7
Phosphorus (mg/dL)	N/A	N/A	N/A	N/A	N/A	N/A	9.9	1.2	6	11.3	0.8	7

N/A, not applicable.