Video gait analysis and measurement of gait angles. (A) Photographs of mouse gait
angles at the toe-off phase of the gait cycle at 236 days postoperatively in normal
control, negative control, hWJ-MSC, and hADSC. The same number of stem cells (5 ×
105) was added in both hWJ-MSC and hADSC groups at postoperative day 0.
(B) Angles were measured in the negative control, hWJ-MSC, and hADSC groups for up to
293 days following transection surgery. The mean ± SD of the negative control,
hWJ-MSC, and hADSC groups were 68.9 ± 3.4°, 68.0 ± 5.8°, and 65.5 ± 10.6°,
respectively, at POD 7. The mean ± SD of the negative control, hWJ-MSC, and hADSC
groups were 59.1 ± 10.8°, 92.4 ± 20.6°, and 77.5 ± 10.3°, respectively, at POD 44. The
mean ± SD of the negative control, hWJ-MSC, and hADSC groups were 58.5 ± 9.3°, 106.8 ±
14.9°, and 82.8 ± 6.4°, respectively, at POD 236. Comparison of mean ± SD of the
negative control with hWJ-MSC and hADSC groups showed a significant difference
(p = 0.0008, one-way ANOVA; negative control vs. hWJ-MSC,
p = 0.0030; negative control vs. hADSC, p =
0.0048; hWJ-MSC vs. hADSC, p = 0.0149; Tukey’s test). The average
angle of the normal mouse group was 128.0° ± 0.8376°.