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. 2019 Sep 11;28(12):1614–1623. doi: 10.1177/0963689719875409

Fig 2.

Fig 2.

Circular matrix metalloproteinase 9 (circ-MMP9) depletion inhibits oral squamous cell carcinoma (OSCC) cell migration and invasion in vitro as well as lung metastasis in vivo. (a) Wound healing assay in circ-MMP9-depleted UM1 and HSC-3 cells. (b) Transwell invasion assay in circ-MMP9-depleted UM1 and HSC-3 cells. (c) A schematic diagram showing the specific process of establishing a lung metastasis model. (d) Representative images showing lung metastasis in vivo monitored by the IVIS system (left), lung tissues, and hematoxylin and eosin staining (middle) in the indicated three groups. The bold T denotes tumor. **p < 0.01, ***p < 0.001.