Table 1.
Association of circular matrix metalloproteinase 9 (circ-MMP9) expression with clinical parameters in 74 patients with oral squamous cell carcinoma (OSCC).
| Parameters | Total (n=74) | circ-MMP9 expression | p value | |
|---|---|---|---|---|
| Low (n=37) | High (n=37) | |||
| Age (years) | ||||
| ≤ 60 | 21 | 11 | 10 | 0.797 |
| > 60 | 53 | 26 | 27 | |
| Sex | ||||
| Male | 36 | 15 | 21 | 0.163 |
| Female | 38 | 22 | 16 | |
| Tumor site | ||||
| Tongue | 58 | 28 | 30 | 0.311 |
| Cheek | 6 | 2 | 4 | |
| Mouth floor | 10 | 7 | 3 | |
| T classification | ||||
| T1–T2 | 39 | 22 | 17 | 0.244 |
| T3–T4 | 35 | 15 | 20 | |
| Lymph node metastasis | ||||
| Negative | 41 | 27 | 14 | 0.002 |
| Positive | 33 | 10 | 23 | |
| TNM stage | ||||
| I–II | 38 | 25 | 13 | 0.005 |
| III–IV | 36 | 12 | 24 | |
circ-MMP9: circular matrix metalloproteinase 9.