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. 2019 Sep 17;28(12):1674–1685. doi: 10.1177/0963689719874048

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — EPC transplantation attenuated histological lung injury in the rat VILI model. The histopathological alteration of lung tissue in the S (A and D), V (B and E), and VE (C and F) groups were analyzed by H&E staining. A-C: 200 × magnification; D-F: 400 × magnification. The histological change in the V group (B and E) revealed a thickened alveolar wall, pulmonary edema, broken alveoli and hemorrhage. EPC transplantation (VE group) clearly mitigated these alterations (C and E). Abbreviations: EPCs, endothelial progenitor cells; H&E, hematoxylin and eosin; S group, sham; V group, VILI; VE group, VILI with EPC transplantation; VILI, ventilator-induced lung injury.