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Combinational analysis was performed using the Chou and Talalay method. Combination Indexes (CI) below 1 were considered to be synergistic. Values calculated using CompuSyn (v 1.4).
| MDA-MB-231 | BT-549 | ||||
|---|---|---|---|---|---|
| Ratio | Ipat+XMD (µmol/L) | CI (Combination index) | Ratio | Ipat+XMD (µmol/L) | CI (Combination index) |
| 1:1 | 0.3+0.3 | 0.69 | 1:1 | 3+3 | 0.44 |
| 3+3 | 0.54 | 10+10 | 0.28 | ||
| 10+10 | 0.14 | ||||
| 1:3 | 0.1+0.3 | 0.11 | 1:5 | 1+5 | 0.23 |
| 1+3 | 0.25 | ||||
