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. Author manuscript; available in PMC: 2019 Dec 21.
Published in final edited form as: Cancer Gene Ther. 2019 Jun 20;27(6):438–447. doi: 10.1038/s41417-019-0112-z

Table 1: Modified Dose Escalation Schema for Arms A & B:

Dose escalation began at dose level 1 for both Arms. The dose for Arm B was de-escalated to dose levels 0 and 0.5 due to elevated liver transaminases.

Dose level Arm A: rF-GM-CSF Arm B: rF-TRICOM
0 N/A 5.67 × 106 PFU
0.5 N/A 2.84 × 107 PFU
1 7.02 × 107 PFU 5.67 × 107 PFU
2 7.02 × 108 PFU 5.67 × 108 PFU
3 1.4 × 109 PFU 1.13 × 109 PFU