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. 2019 Dec 13;10:1486. doi: 10.3389/fphar.2019.01486

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Copyright © 2019 Chen, Xu, Luo, Qiao, Wang, Xu, Li, Zhu and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of thalidomide on the colonic weight and length in mice induced with TNBS. The colonic length and weight of mice from different groups were measured, and treatment with thalidomide showed remarkably effects in TNBS-induced alterations in colonic weight, length and macroscopic scores. The results were expressed as the mean ± SD. **P < 0.01 compared with the sham-1 and sham-2 groups; ^# P < 0.05, ^## P < 0.01 compared with the model group. (A) Macroscopic appearance of colons from each group. (B) Colon length of each group. (C) Colon weight of each group. (D) Macroscopic score of each group.