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. 2019 Dec 13;9:1373. doi: 10.3389/fonc.2019.01373

Figure 3.

Figure 3

Mechanistic target of rapamycin complex 1 (mTORC1) and mitochondrial biogenesis. mTORC1 promotes mitochondrial biogenesis via upregulation of translation genes and moreover via transcriptional regulation of TFAM, ATP50, NRF1, NRF2 genes.