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. 2019 Nov 13;19(1):350–358. doi: 10.3892/ol.2019.11086

Figure 4.

Figure 4.

RAP2A inhibits apoptosis and DNA damage in MGC803/DDP cells. (A) Percentages of apoptotic MGC803/DDP cells with RAP2A siRNA knockdown following DDP treatment. Cell apoptosis following DDP treatment was analyzed via flow cytometry. (B) DNA damage in MGC803/DDP cells with RAP2A siRNA knockdown during DDP treatment. DNA damage was evaluated via Hoechst 33342 staining and flow cytometry. *P<0.05, ##P<0.01 vs. cisplatin+NC group. RAP2A, Ras-related protein Rap-2a; DDP, cisplatin; siRNA, small interfering RNA; NC, negative control.