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. 2019 Dec 19;20:998. doi: 10.1186/s12864-019-6360-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Regulation of immune response as the most relevant pathway in the infested susceptible (S) skin. Regulation of immune response was predicted for the TopDEGs from S hosts after tick infestation, highlighted in cyan. Red circles represent over-expression: higher the value, stronger the intensity of red. Network object symbols follow the Metacore® reference guide according to the protein class (https://portal.genego.com/legends/MetaCoreQuickReferenceGuide.pdf), and their names may occasionally differ between tables and the figure due to the MetaBase®