Table 1.
Intergroup comparisons of differentially expressed genes in the skin of tick-resistant and -susceptible Braford cattle
| Gene Symbol | Ensembl Gene ID | Description | log2 FCa | FDRb |
|---|---|---|---|---|
| ALOX12E | ENSBTAG00000031933 | Bos taurus arachidonate lipoxygenase, epidermal, mRNA. [Source:RefSeq mRNA;Acc:NM_001083532] | 3.17 | 7.10E-071 |
| 3.58 | 1.41E-082 | |||
| ANXA8 | ENSBTAG00000018499 |
Bos taurus annexin A8-like 1 (ANXA8L1), mRNA. [Source:RefSeq mRNA;Acc:NM_174241] |
1.28 | 5.14E-041 |
| 1.34 | 2.16E-042 | |||
| ASIP | ENSBTAG00000034077 | Bos taurus agouti signaling protein, mRNA. [Source:RefSeq mRNA;Acc:NM_206843] | 4.56 | 3.74E-081 |
| 4.74 | 6.12E-092 | |||
| AWAT1 | ENSBTAG00000018839 | Bos taurus acyl-CoA wax alcohol acyltransferase 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001192683] | −9.60 | 1.37E-051 |
| −9.35 | 2.73E-052 | |||
| BOLA | ENSBTAG00000022590 | uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:F1MWX3] | −2.06 | 1.17E-031 |
| 2.20 | 3.93E-042 | |||
| CCS | ENSBTAG00000004343 | Bos taurus copper chaperone for superoxide dismutase, mRNA. [Source:RefSeq mRNA;Acc:NM_001046187] | 1.09 | 2.29E-021 |
| 1.18 | 5.96E-032 | |||
| COL11A1 | ENSBTAG00000021217 |
Bos taurus collagen, type XI, alpha 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001166509] |
−2.04 | 2.41E-021 |
| −2.00 | 2.26E-022 | |||
| CPVL | ENSBTAG00000007146 |
carboxypeptidase, vitellogenic-like [Source:HGNC Symbol;Acc:14399] |
−3.53 | 2.23E-101 |
| −3.28 | 7.47E-092 | |||
| CYP2B6 | ENSBTAG00000003871 |
cytochrome P450, family 2, subfamily B, polypeptide 6 [Source:HGNC Symbol;Acc:2615] |
−6.49 | 1.23E-151 |
| −6.61 | 3.02E-162 | |||
| DGCR6L | ENSBTAG00000047299 | Bos taurus DiGeorge syndrome critical region gene 6 (DGCR6), mRNA. [Source:RefSeq mRNA;Acc:NM_001110446] | 0.96 | 2.12E-021 |
| 1.00 | 9.24E-032 | |||
| DHRS4 | ENSBTAG00000017665 | Bos taurus dehydrogenase/reductase (SDR family) member 4, mRNA. [Source:RefSeq mRNA;Acc:NM_174822] | 2.03 | 9.35E-141 |
| 2.11 | 5.04E-152 | |||
| DPYSL4 | ENSBTAG00000017780 |
Bos taurus dihydropyrimidinase-like 4, mRNA. [Source:RefSeq mRNA;Acc:NM_001163783] |
6.14 | 1.73E-021 |
| ENPP3 | ENSBTAG00000020196 | Bos taurus ectonucleotide pyrophosphatase/phosphodiesterase 3, mRNA. [Source:RefSeq mRNA;Acc:NM_001075923] | 2.65 | 3.29E-051 |
| 2.69 | 2.39E-052 | |||
| FAM174A | ENSBTAG00000045909 | Bos taurus family with sequence similarity 174, member A, mRNA. [Source:RefSeq mRNA;Acc:NM_001206184] | 1.29 | 3.09E-021 |
| 1.47 | 3.50E-032 | |||
| FAM229B | ENSBTAG00000033429 |
Bos taurus protein FAM229B, mRNA. [Source:RefSeq mRNA;Acc:NM_001195067] |
−2.67 | 3.34E-041 |
| −2.70 | 2.29E-042 | |||
| FNBP1L | ENSBTAG00000004383 | formin binding protein 1-like [Source:HGNC Symbol;Acc:20851] | −0.81 | 1.73E-021 |
| −0.78 | 2.87E-022 | |||
| FOS | ENSBTAG00000004322 | Bos taurus FBJ murine osteosarcoma viral oncogene homolog, mRNA. [Source:RefSeq mRNA;Acc:NM_182786] | 3.32 | 6.34E-031 |
| 3.30 | 9.79E-032 | |||
| FUT5 | ENSBTAG00000000414 | Bos taurus fucosyltransferase 5 (alpha (1,3) fucosyltransferase), mRNA. [Source:RefSeq mRNA;Acc:NM_176851] | 2.43 | 1.10E-021 |
| 2.69 | 1.79E-032 | |||
| GAL3ST1 | ENSBTAG00000014232 |
Bos taurus galactose-3-O-sulfotransferase 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001101972] |
1.93 | 1.60E-022 |
| GSTM1 | ENSBTAG00000031788 |
Bos taurus glutathione S-transferase mu 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001083772] |
2.35 | 3.29E-051 |
| 2.45 | 1.28E-052 | |||
| HBG2 | ENSBTAG00000037644 | Bos taurus hemoglobin, gamma 2 (LOC788610), mRNA. [Source:RefSeq mRNA;Acc:NM_001110509] | −4.64 | 1.99E-031 |
| − 4.06 | 2.51E-022 | |||
| IMP3 | ENSBTAG00000012199 | Bos taurus IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast), mRNA. [Source:RefSeq mRNA;Acc:NM_001079588] | 1.50 | 3.34E-091 |
| 1.39 | 9.66E-082 | |||
| KIF23 | ENSBTAG00000009983 |
Bos taurus kinesin family member 23, mRNA. [Source:RefSeq mRNA;Acc:NM_001098038] |
−1.51 | 1.10E-021 |
| −1.39 | 2.72E-022 | |||
| LAMA1 | ENSBTAG00000018160 | laminin, alpha 1 [Source:HGNC Symbol;Acc:6481] | 2.59 | 4.34E-031 |
| 3.18 | 9.21E-052 | |||
| LOC781726 | ENSBTAG00000038366 | LOC781726 protein; Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:A8YXZ3] | 7.31 | 9.21E-061 |
| 7.16 | 2.39E-052 | |||
| MGC140681 | ENSBTAG00000011692 | Bos taurus chromosome 25 open reading frame, human C16orf45 (C25H16orf45), mRNA. [Source:RefSeq mRNA;Acc:NM_001078077] | 3.71 | 2.13E-041 |
| 3.29 | 2.39E-032 | |||
| MOSC2 | ENSBTAG00000016277 | Bos taurus MOCO sulphurase C-terminal domain containing 2, mRNA. [Source:RefSeq mRNA;Acc:NM_001076380] | −1.53 | 3.13E-031 |
| −1.52 | 3.23E-032 | |||
| MSRB3 | ENSBTAG00000044017 | methionine sulfoxide reductase B3 [Source:HGNC Symbol;Acc:27375] | 1.33 | 1.79E-031 |
| 1.31 | 2.14E-032 | |||
| MTHFS | ENSBTAG00000020023 |
Bos taurus 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase), mRNA. [Source:RefSeq mRNA;Acc:NM_001075616] |
−1.17 | 1.41E-021 |
| MYADML | ENSBTAG00000002786 | Bos taurus myeloid-associated differentiation marker-like (LOC781494), mRNA. [Source:RefSeq mRNA;Acc:NM_001101279] | −2.40 | 1.46E-022 |
| ENSBTAG00000034302 | Bos taurus myeloid-associated differentiation marker-like (LOC512150), mRNA. [Source:RefSeq mRNA;Acc:NM_001104975] | 6.33 | 1.67E-032 | |
| ENSBTAG00000040580 | Bos taurus myeloid-associated differentiation marker-like (LOC618633), mRNA. [Source:RefSeq mRNA;Acc:NM_001103302] | −5.88 | 3.24E-022 | |
| NDUFC2 | ENSBTAG00000018188 | Bos taurus NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5 kDa, mRNA. [Source:RefSeq mRNA;Acc:NM_176642] | 1.14 | 7.06E-031 |
| 1.13 | 7.84E-032 | |||
| NENF | ENSBTAG00000000759 |
Bos taurus neudesin neurotrophic factor, mRNA. [Source:RefSeq mRNA;Acc:NM_001076419] |
1.12 | 1.13E-021 |
| 1.06 | 2.32E-022 | |||
| PON3 | ENSBTAG00000034645 |
Bos taurus paraoxonase 3, mRNA. [Source:RefSeq mRNA;Acc:NM_001075479] |
−4.50 | 1.95E-171 |
| −4.43 | 4.40E-172 | |||
| PRODH | ENSBTAG00000047676 |
Bos taurus proline dehydrogenase (oxidase) 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001075185] |
1.51 | 2.56E-021 |
| 1.52 | 2.21E-022 | |||
| RBP1 | ENSBTAG00000020028 |
Bos taurus retinol binding protein 1, cellular, mRNA. [Source:RefSeq mRNA;Acc:NM_001025343] |
1.29 | 2.54E-022 |
| RESP18 | ENSBTAG00000010897 | Bos taurus regulated endocrine-specific protein 18 homolog (rat), mRNA. [Source:RefSeq mRNA;Acc:NM_001077897] | 6.70 | 7.27E-051 |
| 6.57 | 5.44E-042 | |||
| SAA3 | ENSBTAG00000022396 |
Bos taurus serum amyloid A 3, mRNA. [Source:RefSeq mRNA;Acc:NM_181016] |
5.05 | 3.24E-021 |
| 5.55 | 1.28E-022 | |||
| SAO | ENSBTAG00000001041 |
Bos taurus amine oxidase, copper containing 3, mRNA. [Source:RefSeq mRNA;Acc:NM_001130764] |
6.46 | 4.22E-031 |
| 5.76 | 1.68E-022 | |||
| SIRT5 | ENSBTAG00000014904 |
Bos taurus sirtuin 5, mRNA. [Source:RefSeq mRNA;Acc:NM_001034295] |
1.14 | 1.18E-031 |
| 1.16 | 8.01E-042 | |||
| SLC6A16 | ENSBTAG00000030543 | solute carrier family 6, member 16 [Source:HGNC Symbol;Acc:13622] | 4.50 | 6.55E-031 |
| 4.60 | 3.83E-032 | |||
| SYT5 | ENSBTAG00000002522 |
Bos taurus synaptotagmin V, mRNA. [Source:RefSeq mRNA;Acc:NM_001083744] |
1.85 | 4.83E-031 |
| 1.67 | 2.26E-022 | |||
| TACR2 | ENSBTAG00000021664 |
Bos taurus tachykinin receptor 2, mRNA. [Source:RefSeq mRNA;Acc:NM_174469] |
2.34 | 8.25E-031 |
| 2.39 | 5.10E-032 | |||
| TET1 | ENSBTAG00000037756 | tet methylcytosine dioxygenase 1 [Source:HGNC Symbol;Acc:29484] | −2.16 | 4.12E-022 |
| TNMD | ENSBTAG00000021059 |
Bos taurus tenomodulin, mRNA. [Source:RefSeq mRNA;Acc:NM_001099948] |
−3.93 | 3.08E-021 |
| −4.08 | 1.68E-022 | |||
| TNNT3 | ENSBTAG00000022158 |
Bos taurus troponin T type 3 (skeletal, fast), mRNA. [Source:RefSeq mRNA;Acc:NM_001001441] |
−3.77 | 1.68E-022 |
| TTC36 | ENSBTAG00000014899 |
Bos taurus tetratricopeptide repeat domain 36, mRNA. [Source:RefSeq mRNA;Acc:NM_001040515] |
−2.94 | 1.07E-021 |
| −2.70 | 2.72E-022 | |||
| UPK3A | ENSBTAG00000009913 |
Bos taurus uroplakin 3A, mRNA. [Source:RefSeq mRNA;Acc:NM_174709] |
3.11 | 2.26E-022 |
| UTS2R | ENSBTAG00000018170 | urotensin 2 receptor [Source:HGNC Symbol;Acc:4468] | 3.29 | 5.99E-031 |
| WNT7A | ENSBTAG00000001668 | Bos taurus wingless-type MMTV integration site family, member 7A, mRNA. [Source:RefSeq mRNA;Acc:NM_001192788] | 7.10 | 3.67E-021 |
| 7.59 | 1.58E-022 |
alog2 Fold Change
bFalse Discovery Rate
1Resistant vs. Susceptible prior to infestation: Rpre vs. Spre
2Resistant vs. Susceptible post infestation: Rpost vs. Spost