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. 2019 Dec 20;20(Suppl 24):668. doi: 10.1186/s12859-019-3252-0

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — The relationship between expression skewness and differential Methylation in KIRC. The gene expression skewness for the 500 most significant genes identified from the KIRC cohort are plotted against the average change in DNA methylation of their significant annotated methylation sites classified by functional region for a. all probes, b. promoter, c. UTR, d. gene body. The data are split into quadrants representing positive/negative skewness and increase/decrease in methylation. Red points = upper left quadrant, blue = upper right, purple = lower left, green = bottom right