Table I.
Patient characteristics of ES-SCLC with distant metastasis from the SEER Database.
| Characteristics | Total (%) | Radiotherapy (%) | No radiotherapy (%) | P-value |
|---|---|---|---|---|
| Total | 8,595 (100) | 3,397 (39.5) | 5,198 (60.5) | |
| Age, years | <0.001 | |||
| ≤49 | 360 (4.2) | 202 (5.9) | 158 (3.0) | |
| 50–64 | 3,248 (37.8) | 1,486 (43.7) | 1,762 (33.9) | |
| ≥65 | 4,987 (58.0) | 1,709 (50.3) | 3,278 (63.1) | |
| Ethnicity | 0.004 | |||
| White | 7,495 (87.2) | 2,912 (85.7) | 4,583 (88.2) | |
| Black | 767 (8.9) | 337 (9.9) | 430 (8.3) | |
| Other | 333 (3.9) | 148 (4.4) | 185 (3.6) | |
| Sex | 0.710 | |||
| Male | 4,614 (53.7) | 1,832 (53.9) | 2,782 (53.5) | |
| Female | 3,981 (46.3) | 1,565 (46.1) | 2,416 (46.5) | |
| AJCC T stage | <0.001 | |||
| T1 | 755 (8.8) | 331 (9.7) | 424 (8.2) | |
| T2 | 1,809 (21.0) | 699 (20.6) | 1,110 (21.4) | |
| T3 | 1,644 (19.1) | 666 (19.6) | 978 (18.8) | |
| T4 | 3,062 (35.6) | 1,314 (38.7) | 1,748 (33.6) | |
| Tx | 1,325 (15.4) | 387 (11.4) | 938 (18.0) | |
| AJCC N stage | 0.002 | |||
| N0 | 1,006 (11.7) | 397 (11.7) | 609 (11.7) | |
| N1 | 576 (6.7) | 247 (7.3) | 329 (6.3) | |
| N2 | 4,720 (54.9) | 1,840 (54.2) | 2,880 (55.4) | |
| N3 | 1,863 (21.7) | 775 (22.8) | 1,088 (20.9) | |
| Nx | 430 (5.0) | 138 (4.1) | 292 (5.6) | |
| Bone metastasis | 0.258 | |||
| Yes | 3,577 (41.6) | 1,439 (42.4) | 2,138 (41.1) | |
| No | 5,018 (58.4) | 1,958 (57.6) | 3,060 (58.9) | |
| Brain metastasis | <0.001 | |||
| Yes | 2,542 (29.6) | 1,842 (54.2) | 700 (13.5) | |
| No | 6,053 (70.4) | 1,555 (45.8) | 4,498 (86.5) | |
| Lung metastasis | <0.001 | |||
| Yes | 2,137 (24.9) | 736 (21.7) | 1,401 (27.0) | |
| No | 6,458 (75.1) | 2,661 (78.3) | 3,797 (73.0) | |
| Liver metastasis | <0.001 | |||
| Yes | 4,884 (56.8) | 1,346 (39.6) | 3538 (68.1) | |
| No | 3,711 (43.2) | 2,051 (60.4) | 1,660 (31.9) |
ES-SCLC, extensive stage small cell lung cancer; SEER, Surveillance Epidemiology and End Results; AJCC, American Joint Committee on Cancer; T, Tumor; N, Node.