Table 4.
Organ/tissue distribution of pept1a (slc15a1a) and pept1b (slc15a1b) mRNA in teleost fish species for which the expression of the two genes has contemporarily been studied. Whenever co-analyzed pept2 (slc15a2) mRNA expression has also been considered
| Species [order] | Developmental stage | Description | GenBank Acc. No. | Organ/tissue distribution (observed in the study) | Distribution along the post-gastric alimentary canal (observed in the study) | Notes | References |
|---|---|---|---|---|---|---|---|
| Mummichog (Fundulus heteroclitus) [Cyprinodontiformes] | Adults (~ 9 g) | pept1a (slc15a1a) | JN615008.1 | Intestine | Anterior intestine ≈ posterior intestine | Environmental (freshwater acclimation vs. seawater acclimation) and nutritional (fasting vs. re-feeding) regulation of pept1a (slc15a1a) and pept1b (slc15a1b) | [43] |
| pept1b (slc15a1b) | JN615007.1 | Anterior intestine ≈ posterior intestine | |||||
| Nile Tilapia (Oreochromis niloticus) [Cichliformes] | Juveniles (~ 12 g) | pept1a (slc15a1a) | XM_005452882 | Intestine >>> stomach > brain > gill > liver | Proximal intestine >> mid intestine >>> distal intestine | Environmental (waterborne copper exposure) and/or nutritional (fasting vs. re-feeding) regulation of pept1a (slc15a1a), pept1b (slc15a1b) and pept2 (slc15a2) | [44] |
| pept1b (slc15a1b) | XM_005465251 | Intestine >>> brain ≈ stomach | Mid intestine > proximal intestine >>> distal intestine | ||||
| pept2 (slc15a2) | XM_005475385 | Intestine >> stomach > kidney > liver ≥ gill ≈ brain > spleen > muscle | Mid intestine >>> distal intestine > proximal intestine | ||||
| Adults (~ 62 g) | pept1a (slc15a1a) | XM_013267250.1 | Intestine | Anterior intestine > middle intestine >>>> posterior intestine | Environmental (high-salinity acclimation) regulation of pept1b (slc15a1b) | [45] | |
| pept1b (slc15a1b) | XM_005452882.2 | Anterior intestine ≈ middle intestine >>>> posterior intestine | |||||
| pept2 (slc15a2) | XM_005475385 | Posterior intestine > middle intestine >> anterior intestine | |||||
| Adults (~ 125 g) | pept1a (slc15a1a) | XM_003459630 | Intestine | Anterior intestine > middle intestine >>> posterior intestine | Nutritional (dietary salt supplementation) regulation of pept1a (slc15a1a), pept1b (slc15a1b) and pept2 (slc15a2) | [46] | |
| pept1b (slc15a1b) | XM_003447363 | Middle intestine > anterior intestine >>> posterior intestine | |||||
| pept2 (slc15a2) | XM_003454878 | Posterior intestine ≥ middle intestine >> anterior intestine | |||||
| Mozambique tilapia (Oreochromis mossambicus) [Cichliformes] | Adults (~ 97 g) | pept1a (slc15a1a) | XM_003459630 | Intestine | Anterior and middle intestine | Environmental (salinity-dependent) nutritional regulation of pept1a (slc15a1a), pept1b (slc15a1b) and pept2 (slc15a2) | [47] |
| pept1b (slc15a1b) | XM_003447363 | Anterior and middle intestine | |||||
| pept2 (slc15a2) | XM_003454878 | Middle and posterior intestine | |||||
| Adults (100–250 g) | pept1a (slc15a1a) | LC197343 | Intestine | Hepatic loop > proximal major coil >>> gastric loop ≈ distal major coil ≈ terminal segment | Nutritional (fasting vs. re-feeding) regulation of pept1a (slc15a1a) | [48] | |
| Adults (~ 24 g) | pept1a (slc15a1a) | XM_013267250.1 | Intestine | Anterior intestine > middle intestine >>>> posterior intestine | Environmental (high-salinity acclimation) regulation of pept1a (slc15a1a) and pept2 (slc15a2) | [45] | |
| pept1b (slc15a1b) | XM_005452882.2 | Anterior intestine ≈ middle intestine >>>> posterior intestine | |||||
| pept2 (slc15a2) | XM_005475385 | Posterior intestine > middle intestine >> anterior intestine | |||||
| Adults (~ 54 g) | pept1a (slc15a1a) | KX034112.1 | Intestine >>>> pituitary ≈ skin ≈ muscle ≈ kidney ≥ heart ≈ brain ≈ gills ≥ liver ≈ fat ≥ stomach ≈ esophagus ≈ spleen | Anterior intestine >>> middle intestine >> posterior intestine | – | [49] | |
| pept1b (slc15a1b) | KX034110.1 | Intestine >>>> brain > pituitary > muscle > skin ≈ gills ≈ heart ≈ liver ≈ fat ≈ spleen ≈ kidney ≈ esophagus ≈ stomach | Anterior intestine >>>> middle intestine > posterior intestine | ||||
| pept2 (slc15a2) | KX034111.1 | Intestine ≥ kidney >> muscle ≥ liver > brain ≈ pituitary ≈ skin ≈ stomach > heart ≈ spleen ≈ heart > gills | Middle intestine >>>> posterior intestine >> anterior intestine | ||||
| Pre-feeding larvae (3–14 dpf) | pept1a (slc15a1a) | KX034112.1 | Intestine | Whole intestine | Temporal (time course from the pre-hatching to completion of yolk sac resorption stage) regulation of pept1a (slc15a1a), pept1b (slc15a1b) and pept2 (slc15a2) | ||
| pept1b (slc15a1b) | KX034110.1 | ||||||
| pept2 (slc15a2) | KX034111.1 | ||||||
| European seabass (Dicentrarchus labrax) [Perciformes] | Juveniles (~ 1.2 g) | pept1a (slc15a1a) | – | Intestine | Whole intestine | Environmental (short- and long-term low-salinity acclimation) regulation of pept1a (slc15a1a), pept1b (slc15a1b) and pept2 (slc15a2) | [50] |
| pept1b (slc15a1b) | – | ||||||
| pept2 (slc15a2) | – |
Assayed by quantitative real-time PCR, dpf days post-fertilization