Table 1.
Descriptive clinical characteristics of penile cancer
| Characteristics | Total | HPV Positive | HPV MG | P16INK4A+ | ||||
|---|---|---|---|---|---|---|---|---|
| n = 60 | % | n = 56 | 55% | n = 33 | % | n = 55 | 30.9% | |
| Age diagnosis | ||||||||
| ≤ 45 | 8 | 13.3 | 4/7 | 57.1 | 0 | 0.0 | 2/6 | 33.3 |
| 46–55 | 13 | 21.7 | 5/12 | 41.7 | 1 | 20.0 | 0/12 | 0.0 |
| 56–65 | 11 | 18.3 | 5/10 | 50.0 | 3 | 60.0 | 3/10 | 30.0 |
| 66–75 | 12 | 20.0 | 8/12 | 66.7 | 1 | 12.5 | 4/12 | 33.3 |
| ≥ 76 | 14 | 23.0 | 10/13 | 76.9 | 5 | 50.0 | 7/13 | 53.8 |
| ¿? | 2 | 3.3 | 1/2 | 50.0 | 0 | 0.0 | 1/2 | 50.0 |
| Tobacco | ||||||||
| Yes | 16 | 37.2 | 7/15 | 46.7 | 4 | 57.1 | 3/15 | 20.0 |
| No | 27 | 62.8 | 16/25 | 64.0 | 5 | 31.3 | 8/24 | 33.3 |
| Alcohol | ||||||||
| Yes | 10 | 23.3 | 5/9 | 55.6 | 5 | 100.0 | 3/9 | 33.3 |
| No | 33 | 76.7 | 18/31 | 58.1 | 4 | 22.2 | 8/30 | 26.7 |
| p = 0.0037 | ||||||||
| Anatomical region | ||||||||
| Corpus | 2 | 4.1 | 1/2 | 50.0 | 1 | 100.0 | 1/2 | 50.0 |
| Glans | 29 | 59.2 | 15/7 | 55.6 | 3 | 20.0 | 4/6 | 15.4 |
| Prepuce | 6 | 12.2 | 2/6 | 33.3 | 2 | 100.0 | 2/6 | 33.3 |
| Coronal surcus | 2 | 4.1 | 2/2 | 100.0 | 0 | 0.0 | 1/2 | 50.0 |
| Multifocal | 10 | 20.4 | 7/10 | 70.0 | 3 | 42.9 | 5/10 | 50.0 |
| Tumoral size | ||||||||
| < 5 cm | 15 | 36.6 | 10/15 | 66.7 | 4 | 40.0 | 5/15 | 33.3 |
| 5–10 cm | 17 | 41.5 | 10/16 | 62.5 | 1 | 10.0 | 5/15 | 33.3 |
| > 10 cm | 9 | 22.0 | 4/7 | 57.1 | 4 | 100.0 | 2/8 | 25.0 |
| Clinical Stage | ||||||||
| I | 6 | 17.1 | 5/6 | 83.3 | 2 | 40.0 | 1/5 | 20.0 |
| II | 6 | 17.1 | 3/4 | 75.0 | 1 | 33.3 | 2/5 | 40.0 |
| III | 11 | 31.4 | 7/11 | 63.6 | 2 | 28.6 | 3/10 | 30.0 |
| IV | 12 | 34.3 | 5/11 | 45.5 | 1 | 20.0 | 2/11 | 18.2 |
HPV MG HPV Multiple Genotypes