Table 4.
Univariate and multivariate analysis of clinicopathological variables and ENO1 expression associated with overall survival
| Parameters | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Gender | 1.075 (0.688–1.679) | 0.750 | ||
| Age (years) | 1.033 (0.611–1.747) | 0.903 | ||
| Blood glucose (mmol/L)a | 3.082 (1.708–5.558) | < 0.001* | 2.020 (1.067–3.825) | 0.031* |
| Tumor size (cm) | 1.329 (0.852–2.071) | 0.209 | ||
| Differentiation | 1.624 (1.000–2.639) | 0.050 | ||
| Lymph node metastasis | 1.983 (1.159–3.394) | 0.013* | 1.447 (0.646–3.242) | 0.369 |
| Distant metastasis | 5.164 (2.588–10.307) | < 0.001* | 3.063 (1.461–6.424) | 0.003* |
| TNM stage | 1.926 (1.207–3.072) | 0.006* | 1.067 (0.511–2.224) | 0.864 |
| ENO1 expression | 2.310 (1.404–3.800) | 0.001* | 1.867 (1.086–3.209) | 0.024* |
aPreoperative fasting blood glucose
* Statistically significant (P < 0.05)