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. 2019 Nov 8;19(1):177–186. doi: 10.3892/ol.2019.11073

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Copyright: © Mo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Identification of significant modules associated with clinical traits and screening module hub genes. (A) Correlation of module eigengenes with all traits. Each unit contains the corresponding correlation coefficient and P-value. The table is color-coded by correlation according to the color legend. (B) Distribution of TNM stage-related genes in all modules. Modules and enrichment significance are presented on the x- and y-axis, respectively. Scatterplots of GS for metastasis vs. MM in the (C) turquoise and (D) blue modules. The corresponding correlation coefficient and P-value are listed above the scatterplot. The horizontal red lines indicate GS=0.2 and the vertical red lines indicate MM=0.8. TNM, tumor-node-metastasis; GS, gene significance; MM, module membership.