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. 2019 Nov 13;19(1):83–92. doi: 10.3892/ol.2019.11083

Figure 3.

Figure 3.

Curcumin increases intracellular accumulation of RHO-123 and DOX in K562/DOX cells. (A) Effects of VRP (10 µM) and curcumin (0.5, 1 or 2 µM) on intracellular accumulation of RHO-123 was detected by flow cytometry. ‘FL-1H’ means RHO-123 emitting light detection channel, x-axis means fluorescence signal was detected by FL-1H. (B) A quantification of the effect of VRP (10 µM) and curcumin (0.5, 1 or 2 µM) on intracellular accumulation of RHO-123. (C) Effects of VRP (10 Μm) and curcumin (0.5, 1 or 2 Μm) on intracellular accumulation of DOX. **P<0.01, ***P<0.001. DOX, doxorubicin; VRP, verapamil.