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. 2019 Nov 22;19(1):899–907. doi: 10.3892/ol.2019.11140

Figure 4.

Figure 4.

Analysis of the expression of HOXC13 in breast cancer subtypes. (A) HOXC13 expression heatmap of each breast cancer subtype in TCGA from the University of California, Santa Cruz Xena browser. Null data indicates samples that have no gene expression data. (B) HOXC13 expression analysis and mutation status in breast cancer using cBioPortal. HOXC13 was significantly amplified in breast cancer subtypes, including breast invasive carcinoma. The present study included datasets on breast (TCGA2015), breast (TCGA) and breast invasive carcinoma breast (TCGA PanCan) datasets. TCGA, The Cancer Genome Atlas; RNA seq, RNA sequencing; HER2, human epidermal growth factor receptor 2; RPKM, reads per kilobase of transcript per million mapped reads; HOXC13, homeobox C13; VUS, variants of uncertain significance; CNA, copy number alteration.