Table 1.
Results of spatial cytokine-total protein response correlation analysis. Pearson correlation coefficients (r) and significance values (p) for associated cytokines and total protein levels across all sampling locations are listed. N =12 and any outliers driving correlations were identified and removed.
| Cytokine | Total protein | Correlation (r) | p |
|---|---|---|---|
| At fracture | |||
| MIP-1α | CREB | −0.7570 | 0.0112 |
| MIP-1α | MEK1 | −0.7740 | 0.0086 |
| MIP-1α | c-Jun | −0.7447 | 0.0135 |
| MIP-1α | Akt | −0.6485 | 0.0425 |
| IL2 | MEK1 | −0.7521 | 0.0121 |
| TNF-α | MEK1 | −0.7728 | 0.0088 |
| IL-1α | MEK1 | −0.6630 | 0.0367 |
| IL-1α | JNK | −0.6302 | 0.0377 |
| IL-1β | ERK1/2 | −0.6498 | 0.0420 |
| 1-cm Away | |||
| MIP-1α | CREB | −0.7023 | 0.0109 |
| MIP-1α | p38 | −0.5849 | 0.0458 |
| IL2 | CREB | −0.7846 | 0.0025 |
| IL2 | Akt | −0.5873 | 0.0447 |
| Uninjured leg | |||
| IL6 | MEK1 | −0.7139 | 0.0091 |
| IL2 | MEK1 | −0.5944 | 0.0415 |
| IL-1α | Akt | 0.6174 | 0.043 |