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. Author manuscript; available in PMC: 2020 Jul 15.
Published in final edited form as: Clin Cancer Res. 2019 Apr 11;25(14):4375–4387. doi: 10.1158/1078-0432.CCR-18-4144

Figure 4. Activation of PI3K/Akt/mTOR signaling in oligodendroglial tumors and xenografts that harbor alteration in PI3K/Akt/mTOR pathway genes.

Figure 4.

Immunohistochemical analysis demonstrating Ki-67, p-AKT (Ser473), p-4EBP1, and pS6K expression in xenograft generating oligodendroglial tumors and corresponding xenografts (YMG23 and YMG23sc1 (A), YMG5 and YMG5sc1 (B), and YMG137 and MGG137sc1 (C)), and oligodendroglial tumors that did not generate xenografts (YMG28 (D), YMG46 (E), and YMG53 (F)). Bars, 50um.