Table 1.
Characteristics of oligodendroglial tumors used in xenograft assays
| Cell line | Histology | Xenograft-induced lethality |
Mutation in PI3K/Akt/mTOR pathway |
|---|---|---|---|
| YMG5 | AOD | Yes | PIK3R1 I571NfsTer31 |
| YMG6R3T | AOD | Yes | PIK3CA E542K |
| YMG6R4T | AOD | Yes | PIK3CA E542K |
| YMG23 | AOD | Yes | PIK3CA H1047R |
| MGG60 | AOD | Yes | PIK3CA H1047L |
| MGG137 | AOD | Yes | mTOR S2215F |
| YMG6R3F | AOD | No | None |
| YMG28 | AOD | No | None |
| YMG46 | OD | No | PIK3CA E469G |
| YMG53 | AOD | No | None |
| MGG78 | OD | No | None |
| MGG82 | AOD | No | None |
| MGG109 | AOD | No | None |
| MGG126 | AOD | No | None |
| MGG130 | AOD | No | None |