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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Neurobiol Aging. 2019 Oct 14;85:131–139. doi: 10.1016/j.neurobiolaging.2019.10.003

Figure 4.

Figure 4.

Regional myelin water fraction (MWF) trajectories as a function of age. For each ROI, the coefficient of determination, R2, and the significance of the linear regression model, p, are reported. Gray areas indicate 95% confidence intervals. All regions investigated show an inverted U-shaped trend of MWF with age, but with differences in detail between regions in MWF trajectories with age. WB: whole brain white matter, FL: frontal lobes, PL: parietal lobes, OL: occipital lobes, TB: temporal lobes, CRB: cerebellum, SCC: splenium of corpus callosum, BCC: body of corpus callosum, GCC: genu of corpus callosum, IC: internal capsule, ACR: anterior corona radiata, PCR: posterior corona radiata, CP: cerebral peduncle, PTR: posterior thalamic radiation, ATR: anterior thalamic radiation, SFOF: superior fronto-occipital fasciculus, IFOF: inferior fronto-occipital fasciculus, SLF: superior longitudinal fasciculus, ILF: inferior longitudinal fasciculus, FM: forceps major, Fm: forceps minor, Ins: insula, Cau: caudate, Put: putamen, Tha: thalamus, MWF: myelin water fraction.