Table 2.
Significance of regression terms in the linear regression, year of apparent maximum myelination, runs test of randomness, and ANOVA from MWF values across age-intervals.
| Age |
Age2 |
Year of maximum MWF | RTR |
ANOVA |
||||
|---|---|---|---|---|---|---|---|---|
| p | F | p | F | p | p | F | ||
| WB | < 0.01 | 50.4 | < 0.01 | 10.2 | 39.7 | > 0.1 | < 0.01 | 9.9 |
| FL | < 0.01 | 46.6 | < 0.01 | 12.8 | 42.3 | > 0.1 | < 0.01 | 8.7 |
| OL | < 0.01 | 16.7 | < 0.01 | 6.6 | 45.9 | > 0.1 | < 0.01 | 5.3 |
| PL | < 0.01 | 52.1 | < 0.01 | 9.0 | 38.2 | > 0.1 | < 0.01 | 9.6 |
| TL | < 0.01 | 29.2 | < 0.01 | 8.8 | 43.0 | > 0.1 | < 0.01 | 7.0 |
| CRB | < 0.01 | 19.6 | < 0.01 | 7.9 | 45.1 | > 0.1 | < 0.01 | 4.5 |
| BCC | < 0.01 | 29.4 | < 0.05 | 4.4 | 36.7 | > 0.1 | < 0.01 | 6.1 |
| GCC | < 0.01 | 26.2 | > 0.1 | 2.2 | NA | > 0.1 | < 0.01 | 4.2 |
| SCC | < 0.01 | 36.4 | < 0.01 | 9.6 | 42.0 | > 0.1 | < 0.01 | 7.1 |
| IC | < 0.01 | 35.4 | < 0.05 | 4.2 | 33.9 | > 0.1 | < 0.01 | 6.7 |
| ACR | < 0.01 | 60.3 | < 0.05 | 3.4 | 23.3 | > 0.1 | < 0.01 | 10.4 |
| PCR | < 0.01 | 60.5 | < 0.05 | 6.6 | 33.2 | < 0.05 | < 0.01 | 11.1 |
| CP | < 0.05 | 5.7 | > 0.1 | 1.2 | NA | > 0.1 | > 0.1 | 1.4 |
| PTR | < 0.01 | 52.3 | < 0.01 | 7.1 | 35.7 | > 0.1 | < 0.01 | 11.8 |
| ATR | < 0.01 | 43.7 | > 0.1 | 1.7 | NA | < 0.05 | < 0.01 | 8.7 |
| SFOF | < 0.01 | 60.8 | < 0.05 | 4.7 | 28.5 | > 0.1 | < 0.01 | 10.2 |
| IFOF | < 0.01 | 23.4 | < 0.05 | 3.5 | 36.7 | > 0.1 | < 0.01 | 4.2 |
| SLF | < 0.01 | 50.9 | < 0.01 | 6.5 | 35.0 | > 0.1 | < 0.01 | 9.7 |
| ILF | < 0.01 | 21.2 | < 0.01 | 5.3 | 41.5 | > 0.05 | < 0.01 | 4.8 |
| FM | > 0.05 | 3.1 | < 0.05 | 4.0 | 50.7 | < 0.05 | > 0.05 | 1.9 |
| Fm | < 0.01 | 32.3 | < 0.01 | 9.6 | 42.9 | < 0.05 | < 0.01 | 7.4 |
| Cau | > 0.1 | 0.9 | < 0.05 | 6.0 | 54.7 | > 0.1 | > 0.1 | 1.4 |
| Ins | < 0.01 | 24.4 | < 0.01 | 21.1 | 49.2 | > 0.1 | < 0.01 | 6.1 |
| Put | < 0.01 | 7.0 | < 0.05 | 4.9 | 48.1 | > 0.1 | < 0.05 | 2.2 |
| Tha | < 0.01 | 25.5 | < 0.01 | 7.9 | 43.2 | > 0.1 | < 0.01 | 6.3 |
WB: whole brain white matter, FL: frontal lobes, PL: parietal lobes, OL: occipital lobes, TB: temporal lobes, CRB: cerebellum, SCC: splenium of corpus callosum, BCC: body of corpus callosum, GCC: genu of corpus callosum, IC: internal capsule, ACR: anterior corona radiata, PCR: posterior corona radiata, CP: cerebral peduncle, PTR: posterior thalamic radiation, ATR: anterior thalamic radiation, SFOF: superior fronto-occipital fasciculus, IFOF: inferior fronto-occipital fasciculus, SLF: superior longitudinal fasciculus, ILF: inferior longitudinal fasciculus, FM: forceps major, Fm: forceps minor, Ins: insula, Cau: caudate, Put: putamen, Tha: thalamus. RTR: run test of randomness for the model incorporating a quadratic age term, MWF: myelin water fraction. NA indicates not applicable for a non-significant Age2 term. Bold indicates significance. Besides the ANOVA results, all p-values presented are obtained after FDR correction.