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. 2019 Nov 28;19(1):663–670. doi: 10.3892/ol.2019.11151

Figure 4.

Figure 4.

FOXQ1 is a direct target of miR-106a. (A) Sequence alignment of miR-106a with 3′UTR of FOXQ1 mRNA was exhibited. (B) Transfection of miR-106a mimics reduced luciferase activity of 293T cells transfected with FOXQ1 3′UTR-WT. (C) Transfection of miR-106a mimics did not alter luciferase activity of 293T cells transfected with pGL3-FOXQ1-3′UTR-Mut. (D) Transfection of miR-106a mimics reduced luciferase activity of HCT116 cells transfected with FOXQ1 3′UTR-WT. (E) Transfection of miR-106a mimics did not alter luciferase activity of HCT-116 cells transfected with pGL3-FOXQ1-3′UTR-Mut. ***P<0.001, miR-106a mimics vs. miR-NC mimics. miR, microRNA; FOXQ1, Forkhead box Q1; UTR, untranslated region.