ZNF703 silencing in TT cells suppresses xenograft tumor growth. (A) Expression of ZNF703 protein in xenograft tumors from individual mice carrying either TT cells transfected with control-shRNA or TT cells transfected with ZNF703-shRNA was examined by western blotting. Each data point represents the mean ± SD of six xenograft tumors. (B) Volumes of xenograft tumors derived from cells with control-shRNA or ZNF703-shRNA were measured over time. Each data point represents the mean ± SD of six xenograft tumors. (C) Weights of xenograft tumors derived from cells with control-shRNA or ZNF703-shRNA were measured at 30 days. Left, photographs of xenograft tumors. Right, weights of tumors. Each data point represents the mean ± SD of six xenograft tumors. *P<0.05; ***P<0.001. NS, no significance; SD, standard deviation; shRNA, short hairpin RNA; LV, lentiviruses.