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. 2019 Nov 28;19(1):943–951. doi: 10.3892/ol.2019.11153

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — ZNF703 silencing regulates the levels of pAKT⁴⁷³ and p53 protein in vitro and in vivo. (A) Akt, pAKT⁴⁷³ and p53 protein expression in TT cells, with or without ZNF703 silencing, were determined by western blotting. Each data point represents the mean ± SD of three independent experiments. (B) Akt, pAKT⁴⁷³ and p53 protein expression in xenograft tumors, with or without ZNF703 silencing, were determined by western blotting. Each data point represents the mean ± SD of six xenograft tumors. *P<0.05; **P<0.01. NS, no significance; SD, standard deviation; siRNA, small interfering RNA; shRNA, short hairpin RNA.