Table I.

Association between ZNF703 and pAkt⁴⁷³ protein expression and clinicopathological features of patients with MTC.

		ZNF703, n			pAkt473, n
Variable	Total no., n	Negative	Positive	P-value	Negative	Positive	P-value
All cases	46
Normal	12	9	3	0.028	10	2	<0.001
MTC	34	13	21		8	26
Age
≤45 years	11	5	6	0.709	2	9	>0.999
>45 years	23	8	15		6	17
Sex
Male	11	6	5	0.262	1	10	0.227
Female	23	7	16		7	16
Tumor size
≤4 cm	17	10	7	0.013	8	9	0.003
>4 cm	17	3	14		0	17
Lymph node metastasis
−	13	9	4	0.009	7	6	0.002
+	21	4	17		1	20
Disease stage (37)
I, II	13	9	4	0.009	7	6	0.002
III, IV	21	4	17		1	20

ZNF703, zinc finger protein 703; pAkt⁴⁷³, Akt1 protein at serine 473; MTC, medullary thyroid cancer.