Table 1.
Age-standardized characteristics of breast cancer cases by race and ethnicitya in the SEER Cancer Registries (n= 454,154)
| Overall (N=454,154) |
White (N=331,418) |
Black (N=45,218) |
Asian/PI (N=35,623) |
Hispanic (N=41,895) |
|
|---|---|---|---|---|---|
| Breast quadrants | |||||
| Nipple/central portion of breast | 8.6 | 8.5 | 7.7 | 10.3 | 8.9 |
| Upper-inner quadrant | 17.0 | 16.6 | 17.0 | 19.7 | 17.7 |
| Lower-inner quadrant | 8.4 | 8.3 | 9.8 | 8.3 | 8.2 |
| Upper-outer quadrant | 54.3 | 54.9 | 53.4 | 50.6 | 53.6 |
| Lower-outer quadrant | 10.7 | 10.7 | 10.8 | 10.4 | 10.7 |
| Axillary tail of breast | 1.0 | 1.0 | 1.3 | 0.7 | 0.8 |
| Age at diagnosis, mean yearb (SD) | 57.7(11.9) | 58.7(11.7) | 55.2(11.9) | 55.2(11.7) | 54.4(12.1) |
| Age at diagnosis, % | |||||
| 20–39 | 6.3 | 5.1 | 9.4 | 8.7 | 10.8 |
| 40–49 | 20.7 | 18.8 | 24.6 | 26.1 | 26.9 |
| 50–59 | 27.4 | 27.1 | 28.9 | 28.7 | 27.5 |
| 60–69 | 26.2 | 27.6 | 23.0 | 23.1 | 21.6 |
| 70–79 | 19.3 | 21.4 | 14.1 | 13.5 | 13.2 |
| Length of follow-up, mean month (SD) | 105.5(68.4) | 109.4(69.3) | 90.8(63.7) | 103.4(68.7) | 93.9(64.2) |
| Length of follow-up, % | |||||
| 12–59 | 31.8 | 29.6 | 40.1 | 33.6 | 38.3 |
| 60–119 | 30.3 | 30.2 | 30.9 | 30.0 | 30.8 |
| ≥120 | 37.8 | 40.2 | 29.0 | 36.4 | 30.9 |
| Year of diagnosis | |||||
| 1990–1994 | 8.8 | 9.6 | 6.9 | 7.3 | 6.2 |
| 1995–1999 | 11.7 | 12.1 | 9.6 | 12.8 | 9.8 |
| 2000–2004 | 25.4 | 26.2 | 23.6 | 22.0 | 22.9 |
| 2005–2009 | 26.1 | 25.7 | 27.5 | 26.2 | 27.6 |
| 2010–2014 | 28.0 | 26.4 | 32.3 | 31.7 | 33.5 |
| Laterality | |||||
| Right | 49.1 | 49.3 | 48.7 | 49.3 | 48.5 |
| Left | 50.9 | 50.7 | 51.3 | 50.7 | 51.5 |
| Histological subtype | |||||
| Invasive ductal carcinoma | 74.7 | 74.1 | 76.5 | 78.6 | 74.8 |
| Invasive lobular carcinoma | 7.6 | 8.2 | 6.0 | 4.9 | 6.9 |
| Other histology | 17.7 | 17.7 | 17.6 | 16.6 | 18.3 |
| Gradec | |||||
| Well differentiated | 21.4 | 22.8 | 14.2 | 20.1 | 19.1 |
| Moderately differentiated | 42.1 | 43.0 | 36.1 | 43.7 | 41.1 |
| Poorly differentiated and undifferentiated | 36.5 | 34.2 | 49.7 | 36.1 | 39.8 |
| Stage | |||||
| I | 51.1 | 53.3 | 41.4 | 51.1 | 44.9 |
| II | 36.8 | 35.4 | 42.8 | 37.7 | 40.1 |
| III | 12.1 | 11.2 | 15.7 | 11.2 | 15.0 |
| Tumor size, mmd | |||||
| ≤20 | 64.4 | 66.9 | 54.5 | 62.5 | 58.0 |
| 20 – 50 | 30.5 | 28.6 | 37.6 | 32.5 | 35.7 |
| >50 | 5.1 | 4.5 | 7.9 | 5.0 | 6.3 |
| Lymph nodes statuse | |||||
| Negative | 68.1 | 69.2 | 62.6 | 69.9 | 64.0 |
| Positive | 31.9 | 30.8 | 37.4 | 30.1 | 36.0 |
| Estrogen receptorf | |||||
| Negative | 20.8 | 18.9 | 33.7 | 19.4 | 22.5 |
| Positive | 79.2 | 81.1 | 66.3 | 80.6 | 77.5 |
| Progesterone receptorg | |||||
| Negative | 30.9 | 28.9 | 44.4 | 29.4 | 32.9 |
| Positive | 69.1 | 71.1 | 55.6 | 70.6 | 67.1 |
| Hormone receptorh | |||||
| Negative (ER-&PR-) | 19.2 | 17.4 | 31.7 | 17.9 | 20.9 |
| Positive (ER+/PR+) | 80.8 | 82.6 | 68.3 | 82.1 | 79.1 |
| Surgeryi | |||||
| None | 1.3 | 1.0 | 2.7 | 1.4 | 2.1 |
| Breast-conserving surgeryj | 59.3 | 60.4 | 57.0 | 53.2 | 57.1 |
| Mastectomyk | 39.4 | 38.5 | 40.2 | 45.4 | 40.9 |
| Radiation | |||||
| No/unknown | 44.7 | 43.5 | 47.4 | 48.4 | 49.1 |
| Yes | 55.3 | 56.5 | 52.6 | 51.6 | 50.9 |
| Chemotherapy | |||||
| No/unknown | 57.0 | 58.4 | 49.7 | 57.3 | 53.7 |
| Yes | 43.0 | 41.6 | 50.3 | 42.7 | 46.3 |
SD standard deviation
Values are means (SD) or percentages and are standardized to the age distribution of the overall study population in race/ethnicity groups
P values were calculated from a comparison across all groups except the groups with missing values
Values were not age adjusted.
Overall missing: 35,403, White:26,563, Black:3,716, Asian/PI:2,325, Hispanic:2,799
Overall missing: 5,250, White: 3,480, Black: 704, Asian/PI: 507, Hispanic: 559
Overall missing: 509, White:348, Black:82, Asian/PI:24, hispanic:55
Overall missing: 34,545, White:24,827, Black:3,831, Asian/PI:2,295, Hispanic:3,592
Overall missing:40,300, White: 28,865, Black: 4,376, Asian/PI: 2,821, Hispanic: 4,238
Overall missing: 40,572, White: 29,070, Black: 4,402, Asian/PI: 2,838, Hispanic: 4,262
Overall missing: 606, White: 442, Black: 85, Asian/PI: 33, Hispanic: 46
Breast-conserving surgery consisted of excisional biopsy, lumpectomy, nipple resection, wedge resection, quadrantectomy, segmental mastectomy, tylectomy, and partial mastectomy, NOS
Mastectomy included total mastectomy, modified radical mastectomy, radical mastectomy, subcutaneous mastectomy and mastectomy, not otherwise specified