Table 1.
Baseline characteristics on univariate analysis with the presence of esophageal varices.
| Parameters | No Esophageal Varices (n=14) | Esophageal Varices (n=188) | p |
|---|---|---|---|
| Age (in years) | 42.93±7.93 | 43.84±10.10 | 0.6912 |
| Alcohol consumption per day (in grams) | 29 (29–58) | 58 (58–115) | 0.0559a |
| Duration of alcohol intake (in years) | 10.00±2.72 | 12.52±3.69 | 0.0050 |
| Hemoglobin (g/dL) | 8.93±2.37 | 8.26±2.25 | 0.3272 |
| Total leukocyte count (103/μL) | 8805 (5760–14000) | 7175 (5120–9630) | 0.2083a |
| Platelets (109/L) | 158.50 (112–307) | 134 (80–201) | 0.1477a |
| Total Bilirubin (mg/dL) | 2.70 (0.80–11) | 2.60 (1.4–4.5) | 0.4305a |
| Total protein (g/dL) | 6.46±0.55 | 6.55±0.81 | 0.5880 |
| Serum albumin (g/dL) | 2.86±0.56 | 2.80±0.44 | 0.6856 |
| Alanine aminotransferase (ALT) (U/L) | 32.50 (20–43) | 29 (22–46) | 0.2510a |
| Aspartate aminotransferase (AST) (U/L) | 64 (43–92) | 64 (43.5–94.5) | 0.6774a |
| Prothrombin time (sec) | 17.46±3.18 | 19.19±4.22 | 0.0727 |
| Creatinine (mg/dL) | 0.90 (0.7–1.2) | 1.00 (0.8–1.2) | 0.3185a |
| Spleen Bipolar Diameter (mm) | 11.26±2.13 | 13.32±2.45 | 0.0034 |
| CTP score | 9.79±2.49 | 10.31±2.05 | 0.4549 |
| MELD | 16.71±8.77 | 16.22±5.62 | 0.8281 |
| AAR | 2.24±0.98 | 2.21±1.22 | 0.9131 |
| APRI | 1.08±0.73 | 1.70±2.59 | 0.0263 |
| FIB-4 | 3.13 (1.59–5.05) | 3.93 (2.28–6.06) | 0.0825a |
| PC/SD ratio | 1221.50 (878–2743) | 974.50 (614–1655) | 0.0764a |
a
p-values from Mann-Whitney’s U test. All other p-values are from Student’s t-test.
CTP score: Child-Turcotte-Pugh score; MELD: model for end-stage liver disease; AAR: aspartate-aminotransferase-to-alanine-aminotransferase (AST-to-ALT) ratio; APRI: AST-to-platelet-ratio index; FIB-4: fibrosis-4-index; PC/SD: platelet-count-to-spleen-diameter ratio.