Table 1:

DLS and zeta potential measurements of SPIONs at various stages of fabrication indicate success of functionalization. As expected, particle size increases with the addition of each surface modification. Additionally, zeta potential changes reflect the change in surface groups at each stage. Data presented as mean of 3 independent runs of particle fabrication.

Fabrication Stage	Effective Diameter (nm)	Zeta Potential (mV)
CA-SPIONs	13.2	−35.1
PEG-SPIONs	19.2	−11.4
HABP-SPIONs	20.5	−30.8
OPN-SPIONs	25.1	−31.3