Fig. 5. Dose-dependent toxicity of QD-PEG-OH and QD-PEG-OMe in ex vivo OWH slices. Treatment of QD-PEG-OH (red) and QD-PEG-OMe (blue) at 0.01, 0.1, and 1 μM concentrations in P14 rat organotypic brain slices for 24 h. QD toxicity was determined by LDH assay at 0, 1, 2, 4, 8, and 24 h as follows. For each QD concentration, n = 3 slices per QD per concentration condition were evaluated; for NT group (black), n = 5 slices.
