Skip to main content
. Author manuscript; available in PMC: 2019 Dec 20.
Published in final edited form as: Epigenomes. 2016 Sep 22;1(1):2. doi: 10.3390/epigenomes1010002

Figure 5.

Figure 5.

SST1 demethylation changes histone modifications in CRC] cell line HCT116. (A) SST1 methylation levels of individual clones estimated by bisulfite sequencing. Untreated (Unt) or treated with 5-aza-dC at 2.5 μM (AZA); and (B) SST1 demethylation, induced by 5-aza-dC (AZA) treatment (2.5 mM), is followed by an increase in H3K27me3 levels as shown by chromatin immunoprecipitation. H3K9me3 and H3K27me3 levels shown as fold enrichment relative to the input. IgG indicate immunoprecipitation background levels.