Fig 5. Functional tests.

Performance on the cylinder rearing test and the object recognition test at 2 and 5–6 weeks after HI. (a) Results from the cylinder rearing test. The HI animals had a right forepaw preference compared to sham at 2 and 5 weeks after HI. Results are presented in mean ± SE. (b) Boxplots showing the results from the novel object recognition test. The difference in exploration time for the novel and old object, D1, was used as a measure of novel object preference. A positive D1 value indicates a preference for the novel object and a negative D1 value indicates a preference for the old object. The animals showed a preference for the novel object only at 6 weeks after HI. HI, hypoxia-ischemia; MEL, melatonin; sham, sham-operated animals; VEH, vehicle-treated.