Table 1. Individual characteristics of the 27 patients enrolled in the study.
Pt Num | Sex | Age | Site | LI | IAT | CSM | Hand | IQ |
---|---|---|---|---|---|---|---|---|
1 | F | 37 | L | 0.56 | L | L | R | 89 |
2 | M | 21 | L | 0.40 | L | L | R | 97 |
3 | M | 39 | L | 0.52 | n/a | L | R | 100 |
4 | F | 38 | L | 0.27 | L | L | R | 96 |
5 | M | 17 | L | 0.43 | L | L | L | 67 |
6 | F | 30 | L | 0.56 | L | L | R | 107 |
7 | F | 20 | L | 0.72 | n/a | L | R | 103 |
8 | F | 30 | L | 0.82 | L | L | R | 100 |
9 | F | 20 | L | 0.28 | n/a | L | R | 97 |
10 | F | 42 | L | 0.80 | L | L | R | 107 |
11 | F | 28 | L | 0.77 | L | L | R | 97 |
12 | F | 51 | L | 0.19 | L | L | R | 92 |
13 | M | 42 | L | 1.00 | L | L | R | 109 |
14 | M | 23 | L | 0.89 | L | L | R | 91 |
15 | F | 29 | L | 0.46 | L | n/a | R | 84 |
16 | F | 45 | L | n/a | n/a | L | R | 93 |
17 | F | 21 | L | n/a | n/a | L | R | 78 |
18 | M | 30 | R | 0.44 | L | n/a | R | 90 |
19 | M | 27 | R | 0.78 | n/a | Neg | R | 112 |
20 | M | 40 | R | 0.84 | L | n/a | R | 94 |
21 | F | 51 | R | 0.91 | L | n/a | R | 74 |
22 | F | 28 | R | 0.30 | n/a | n/a | L | 107 |
23 | F | 62 | B | 0.33 | L | n/a | R | 93 |
24 | M | 56 | B | 0.79 | n/a | Neg | R | 116 |
25 | M | 24 | B | n/a | L | n/a | R | 105 |
26 | F | 30 | B | 0.24 | n/a | n/a | R | 120 |
27 | F | 31 | B | n/a | L | L | R | 124 |
In 17 subjects, electrode implantation was solely over the left (L) hemisphere; in 5 subjects, it was over the right (R), and in 5 subjects, SDEs were placed bilaterally (B). Laterality indices (LI) were computed using fMRI during the same language tasks (n = 23). LI >0 implies left hemisphere dominance for language. In 18 subjects, the intra-carotid amytal test (IAT) was used to determine language laterality. Cortical stimulation mapping (CSM) was performed in 19 subjects, of which, 17 mapped over the left hemisphere and two over the right (nos. 19 and 24). In all tested subjects, either deficits were produced on the left (L), or they were not observed on the right (Neg). The Edinburgh Handedness Inventory revealed that 25 subjects were right-hand dominant, and 2 were left-hand dominant.