Table 1.
Data and sample collection schedule
Infant age | Antenatal | 0–10 d | 3 m | 6 m | 9 m | 1 y | 1.5 y | 2 y | 2.5 y | 3 y | 3.5 y | 4 y | 4.5 y | 5 y |
Recruitment and randomisation | ||||||||||||||
Eligibility check and consent | ✓ | ✓ | ||||||||||||
Baseline questionnaire | ✓ | ✓ | ||||||||||||
Birth questionnaire | ✓ | |||||||||||||
Randomisation±vaccination | ✓ | |||||||||||||
Full blood examination | ✓* | |||||||||||||
Post randomisation | ||||||||||||||
Perinatal hospital data | ✓ | |||||||||||||
Parent questionnaire | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
Clinical eczema assessment | ✓ | ✓ | ||||||||||||
Skin prick test | ✓ | ✓ | ||||||||||||
Oral food challenge | ✓† | ✓† | ||||||||||||
Biological sample collection | ✓‡ | ✓§ | ✓ | ✓ |
*Soon after birth.
†If indicated by skin prick test result.
‡7±4 days postrandomisation.
§5–8 months of age.
d, days; m, months; y, year.